Gelatinase and Vulnerability of Atherosclerotic Plaque
نویسندگان
چکیده
منابع مشابه
Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability
PURPOSE OF REVIEW Atherosclerotic plaque rupture and subsequent acute events, such as myocardial infarction and stroke, contribute to the majority of cardiovascular-related deaths. Calcification has emerged as a significant predictor of cardiovascular morbidity and mortality, challenging previously held notions that calcifications stabilize atherosclerotic plaques. In this review, we address th...
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Developing imaging technologies capable of identifying unstable atheromatous plaques in vivo is a major issue of clinical cardiovascular research. These techniques would permit an earlier surgical or medical therapy and would anticipate acute ischemic syndromes. Plaque vulnerability depends on the relative amount and thickness of its lipid core and fibrous cap. Several means of assessing athero...
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BACKGROUND Growth of atherosclerotic plaques is accompanied by neovascularization from vasa vasorum microvessels extending through the tunica media into the base of the plaque and by lumen-derived microvessels through the fibrous cap. Microvessels are associated with plaque hemorrhage and may play a role in plaque rupture. Accordingly, we tested this hypothesis by investigating whether microves...
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Objective(s): Cardiovascular disease is a leading cause of morbimortality with over half cardiovascular events occurring in the asymptomatic population by traditional risk stratification. This preliminary study aimed to evaluate systemic plaque vulnerability in patients with prior Coronary Artery Disease (CAD) with a single Whole Body [FDG] PET-CT scan in terms of plaq...
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Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at sites of blood flow disturbance. The disease usually remains silent until a breakdown of integrity at the arterial surface triggers the formation of a thrombus. By occluding the lumen, the thrombus or emboli detaching from it elicits ischaemic symptoms that may be life-threatening. Two types of surface da...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2016
ISSN: 1340-3478,1880-3873
DOI: 10.5551/jat.ed048